National Physical Therapy Examination (NPTE) Practice Exam 2026 - Free NPTE Practice Questions and Study Guide

The correct answer highlights that during the inflation phase of intermittent pneumatic compression, there is an increase in interstitial tissue pressure and venous blood flow.

When the compression device inflates, it exerts pressure on the limb, which serves to compress the venous system. This action increases the pressure in the interstitial space, which can help to push excess fluid out of these areas. The elevation of interstitial tissue pressure provides a driving force that fosters the return of blood to the central circulation, enhancing venous blood flow.

The increase in venous blood flow is significant because it aids in the reduction of edema, improves circulation, and promotes tissue perfusion. This is particularly beneficial in conditions where venous return is compromised, such as in post-surgical recovery or various venous insufficiency scenarios.

Thus, the physiological changes that occur during this phase of pneumatic compression support better circulation and fluid management in the affected limb.